Aris Paschalidis

Aris Paschalidis

Orthopaedic Surgery Resident

Temple University Health

About Me

I am an orthopaedic surgery resident at Temple University Hospital and a graduate of UMass Chan Medical School. My interests lie at the intersection of clinical medicine, data science, and artificial intelligence, with a focus on improving clinical decision-making and patient care.

My background is in computational biology and bioinformatics. Before medical school, I studied computational biology at Brown University and worked as a bioinformatician in the Bailey Lab, developing software to study the genetics and genomics of infectious disease and immunity.

Download my curriculum vitae.

Interests
  • Health AI
  • Digital Medicine
  • Precision Medicine
  • Predictive Modeling
  • Bioinformatics
  • Patient Reported Outcome Measures (PROMs)
Education

  • Resident Physician, 2031

    Temple University Hospital

  • Doctor of Medicine, 2026

    UMass Chan Medical School

  • Bachelor of Science in Computational Biology, 2021

    Brown University

Recent Publications

Huitong Ding, Zehao Ye, Aris Paschalidis, David A. Bennett, Rhoda Au, Honghuang Lin. Dynamic Lifetime Risk Prediction of Alzheimer's Disease with Longitudinal Cognitive Assessment Measurements. Alzheimer’s & Dementia, 2025.
Cite DOI
Robert T.T. Shepard, Aris Paschalidis, Daniel Chen, Neill Li. Metabolic And Non-Pharmacological Modalities Involved In The Growth And Viability Of Peripheral Nerves Following Surgical Repair: A Systematic Review. Presented at: Orthopaedic Research Society Annual Meeting, 2025.
Cite Poster
Wenjie Li, Wenyi Mei, Hewei Jiang, Jie Wang, Xiaoli Li, Lina Quan, Yanyan Diao, Yanni Ma, Sisi Fan, Zhuwei Xie, Mengdie Gong, Huan Zhu, Dewen Bi, Feng Zhang, Lei Ma, Jian Zhang, Yufeng Gao, Aris Paschalidis, Honghuang Lin, Fangfang Liu, Kangdong Liu, Mingliang Ye, Zhenjiang Zhao, Yajun Duan, Zhuo Chen, Yufang Xu, Weilie Xiao, Shengce Tao, Lili Zhu, Honglin Li. Blocking the PD-1 Signal Transduction by Occupying the Phosphorylated ITSM Recognition Site of SHP-2. Science China Life Sciences, 2025.
Cite DOI
Aris Paschalidis, Constantine S. Velmahos, Giorgio Giatsidis. In Autologous Breast Reconstruction, Machine Learning Models Are Poor Predictors of Post-Surgical Morbidity: A Retrospective Cohort Study on a National Database. Presented at: Plastic Surgery The Meeting, 2024.
Cite
Mehdi S. Salimy, Aris Paschalidis, Jacquelyn Dunahoe, Antonia F. Chen, Kyle Alpaugh, Hany S. Bedair, Christopher M. Melnic. Time to Achieve the Minimal Clinically Important Difference in Primary Total Hip Arthroplasty: Comparison of Anterior and Posterior Surgical Approaches. The Journal of Arthroplasty, 2024.
Cite DOI
See all publications

Projects

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All R Packages Genomics Malaria
COI Around the World
COI Around the World

Complexity of infection (COI) in Plasmodium falciparum around the world using coiaf.
coiaf
coiaf

Complexity of infection estimation with allele frequencies.
MIPTools
MIPTools

A suite of computational tools used for molecular inversion probe design, data processing, and analysis.
miplicorn
miplicorn

A unified framework for molecular inversion probe and amplicon analysis.
CAvaccines
CAvaccines

Analyzing the relationship between vaccination rates and infectious disease incidence in California counties.
UCIData
UCIData

A package for accessing UCI Machine Learning Repository data sets inside Julia.
nof1gen
nof1gen

Analysis of N of 1 clinical trials.

Recent Blogs

Convolutional Neural Networks
In its most basic form, a neural network is a set of multilayered, interconnected nodes, often referred to as neurons. Each neuron receives input from neurons in the previous layer, performs a computation, and passes the result to the neurons in the next layer.
Last updated on July 30, 2023 Blogs
Convolutional Neural Networks
Power Analysis
A brief introduction to power analysis.
Last updated on July 27, 2023 Blogs
Why Use OOP?
R is traditionally a functional programming language, meaning that when we code in R, we tend to think in terms of functions. For instance, given a data set, what function can I create to plot a certain variable?
Last updated on February 21, 2022 Blogs
Why Use OOP?
Using R with Git and Github
A demonstration on how to use R with Git and Github.
Last updated on February 21, 2022 Talks
Using R with Git and Github

Contact

  • 3401 N. Broad Street, Philadelphia, PA 19140